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Magnesium Sulfate, per 500 mg Magnesium Sulfate 10%, 20 ml Magnesium Sulfate 50%, 2 ml Mannitol, 25% in 50 ml Mazicon Flumazenil ; , 5 ml Medroxyprogesterone Acetate for Contraceptive use, 150 mg Medroxyprogesterone Acetate, up to 100 mg Meperidine & Promethazine HCL, up to 50 mg Meperidine, Hydrochloride, per 100mg Mephentermine Sulfate, up to 30 mg Mepivacaine Metaraminol, up to 10 mg Methadone HCL, up to 10 mg Methicillin Sodium, up to 1 gram Methocarbamol, up to 10 ml Methotrimeprazine, up to 20 mg Methoxamine, up to 20 mg Methyldopate HCL, up to 250 mg Methylergonovine Maleate, up to 0.2 mg Methylprednisolone Acetate, 20 mg Methylprednisolone Acetate, 40 mg Methylprednisolone Acetate, 80 mg Methylprednisolone Sodium Succinate, up to 40 mg Methylprednisolone Sodium Succinate, up to 125 mg Metoclorpramide HCL, up to 10 mg Metocurine Iodine, up to 2 mg Metronidazole, 500 mg Midazolam Hydrocholoride, per 1 mg Milrinone Lactate, per 5 ml Morphine Sulphate, 100 mg Morphine Sulfate preservative-free sterile solution ; , per 10 mg
Yohko Tanimoto Yakugaku Tosyokan, 42 1 ; , 33 ` 40, 1997 We introduced the Ovid MEDLINE CD-ROM to a stand alone system at the Central Research Laboratories of AJINOMOTO in October 1994. One of the merits of introducing the CD-ROM includes the fact that end-users can retrieve thorough information from the MEDLINE CD-ROM without time restrictions. Compared to other MEDLINE CD-ROM products, the Ovid MEDLINE CD-ROM offers controlled vocabulary mapping capabilities, mouse-click entry for easy operation and the full MEDLINE database on only ten CD-ROM discs. In addition, the retrieval cost of the MEDLINE database is reduced.
LOUISIANA MEDICAID MANAGEMENT INFORMATION SYSTEM DEPT OF HEALTH AND HOSPITALS - BUREAU OF HEALTH SERVICES FINANCING LOUISIANA MEDICAID PHARMACY BENEFITS MANAGEMENT UNIT ONLY THESE DOSAGE FORMS ARE COVERED AND ONLY IF FROM VENDOR LISTED IN APPENDIX C LIST OF DRUG PAYABLE ON DRUG FILE - * LMAC ; EFF. DATE CURR LMAC EFF. DATE 000000 000000 020501 000000 000000 000000 000000 050701 000000 000000 000000 000000 000000 000000 000000 000000 000000 000000 000000 000000 000000 000000 050508 050701 000000 000000 000000 000000 000000 000000 000000 000000 000000 000000 050701 000000 050701 000000 000000 000000 050701 000000 000000.
Thus, capsules, tablets, and lozenges are administered via the oral route unless otherwise indicated by the title. Examples: Acetaminophen Capsules Aminophylline Delayed-Release Tablets Aspirin Extended-Release Tablets Hexylresorcinol Lozenges Meperidine Hydrochloride Tablets Drugs that are injected may be administered via the intravenous, intramuscular, subcutaneous, etc., route; the route being specified in the labeling rather than in the name. Examples: Aurothioglucose Injectable Suspension Epinephrine Injection Fluorouracil Injection Hydrocortisone Acetate Injectable Suspension Phytonadione Injectable Emulsion Creams, ointments, lotions, and pastes are applied topically, unless otherwise indicated by the name. Examples: Benzoyl Peroxide Lotion Betamethasone Dipropionate Cream Estradiol Vaginal Cream Nystatin Ointment Zinc Oxide Paste.
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And intensive care settings, the potential risk of lifethreatening hypertensive crisis can develop when combining MAOIs with indirect-acting sympathomimetics 6, 7 ; . In such situations, it has been suggested to use small doses of directly acting sympathomimetits should vasopressors become necessary 9 ; and, if hypertension occurs, to be ready with P-adrenergic blockers or nitrates 10 ; . The literature on the possible interaction of MAOIs with opioids is also sparse and unclear. There are only a few reports, with conflicting conclusions, regarding the effects of opioids on patients taking MAOIs. The administration of meperidine in patients taking MAOIs has been reported to cause agitation, excitement, restlessness, hypertension, convulsions, and hyperpyrexia 11 ; . MAOIs potentiate the analgesic effect of opioids attributed to inhibition of hepatic opioid metabolism. Thus, it is recommended that one fourth to one fifth of the usual dose of narcotics be used for patients who must receive them 12, 13 ; . Potentiation and prolongation of effect have been reported for meperidine, morphine, pentazocine, pentobarbital, amylbarbital, and thiopental 14 ; . On the other hand, reports of human and animal studies reveal no adverse responses when opioids were administered to patients receiving MAOIs 15, 161. Moreover, Braverman et al. 17 ; reported that fentanyl administration did not result in differences in awakening time or untoward cardiovascular effects in dogs that received MAOIs. Although we remain concerned about adverse drug interactions between MAOIs and indirect-acting sympathomimetic drugs as well as anesthetics, there is limited justification for the discontinuation of MAOIs prior to elective surgery or procedures requiring general anesthesia. Unfortunately, there are very few studies that report on discontinuation of these drugs in patients who are scheduled to receive general anesthesia 15 ; . Michaels et al. 16 ; described two cases of cardiac surgery in which the ritual two- to threeweek period of MAO1 discontinuation had not occurred-one emergent and the other elective surgery. Their first case involved a three-month history of MAO1 phenelzine ; use with discontinuation only 36 hours prior to surgery. The second case involved a patient who received a MAO1 for two and a half years that was discontinued nine days prior to surgery. Both cases were marked by the lack of hemodynamic compromise from drug interaction related to MAOIs. The authors concluded that appropriate monitoring and preparation may obviate the need for withdrawal of MAOIs prior to surgery. El-Ganzouri et al. 15 ; evaluated patients who were maintained on MAOIs and presented for electroconvulsive therapy or elective.
The cardiac-accelerating effects of 0.6 mgm of atropine administered intravenously were tested in 111 patients three groups of 37 patients each ; . The patients in Group "A" received pentobarbitone and diphenhydramine orally before the atropine injection; those in Group "B" received no medications and those in Group "C" received pentobarbitone orally and meperidine intramuscularly. For the purpose of greater precision the time elapsed between ten consecutive electrical systoles was taken as the measure of the heart rate. Measurements were carried out before and two minutes after atropine injection. The control mean heart rate was slower in Group "C" and faster in Group "A". Atropine increased the heart rate of all patients, most of those in Group "C" and and mephenytoin.
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Who serve as their own controls, all variables cannot be eliminated when studying analgesics in the post-operative patient. For instance, the quality of post-operative pain varies considerably from patient to patient due to several factors, such as age, sex, the surgical procedure, the physician-patient relationship and the psychological makeup of the patient. With regard to this last factor, the patient's reaction to illness or injury and the impact that it has on his life situation are additional contributing factors. For these reasons, an attempt was made to eliminate at least one variable by having all pain evaluations recorded by one trained observer. In addition, the premedication and anaesthetic techniques were for the most part similar. Patients undergoing major abdominal or major orthopedic procedures were selected for this study since it is after these operations that many patients experience moderate to severe pain. Since it is our customary practice to use small intravenous doses of meperidine in the recovery room, it was not surprising to us that a high percentage of patients receiving the low dose of both test agents requested additional medication. The smaller butorphanol tartrate doses 0.5 mg and 1.0 mg ; and all meperidine doses 20 mg and 40 mg ; produced adequate analgesia with approximately a two-hour duration of action. The largest dose of butorphanol tartrate 2.0 mg ; produced analgesia of longer duration and produced somewhat more sedation. It was also of interest that, with the exception of one patient who received 0.5 mg of butorphanol tartrate, no clinically significant post-operative respiratory.
Before taking this medication, tell your doctor if you are taking any of the following medicines: tricyclic antidepressants such as amitriptyline elavil, endep ; or doxepin sinequan ; , which maydecrease decrease and drugs interaction ; the effects of reserpine and chlorothiazide; othercommonly see also commonly ; used tricyclic antidepressants, including amoxapine ascendin ; , clomipramine anafranil ; , desipramine norpramin ; , imipramine tofranil ; , nortriptyline pamelor ; , and protriptyline vivactil digoxin lanoxin ; or quinidine cardioquin, quinidex, quinora, quinaglute ; , which will increase the risk that you will experience an irregular heartbeat when it is taken with chlorothiazide and reserpine; barbiturates such as phenobarbital luminal, solfoton ; , amobarbital amytal ; , and secobarbital seconal ; , which may cause extreme sleepiness or dizziness if taken with reserpine and chlorothiazide; narcotic pain relievers such as codeine tylenol #3, tylenol #4, others others and drugs interaction , propoxyphene darvon, darvocet, wygesic ; , oxycodone percodan, percocet, tylox ; , meperidine demerol ; , morphine ms contin, duramorph, others ; , and others, which also may cause extreme sleepiness or dizziness if taken with reserpine and chlorothiazide; steroid medications such as hydrocortisone hydrocortone, cortef ; , prednisone deltasone, orasone ; , prednisolone delta cortef, prelone ; , methylprednisolone medrol ; , betamethasone celestone ; , dexamethasone decadron, hexadrol ; , and others, which may increase the side effects of chlorothiazide; prescription and over-the-counter cough, cold, allergy, diet, and sleeping pills, any of which may contain drugs that increase your blood pressure and heart rate and thus decrease the effects of reserpine; the cholesterol-lowering drugs cholestyramine questran ; and colestipol colestid ; , which may decrease the effects of chlorothiazide; nonsteroidal anti-inflammatory drugs nsaids ; such as ibuprofen motrin, advil ; , ketoprofen orudis, orudis more orudis ; , kt, oruvail ; , and naproxen naprosyn, anaprox, aleve ; , which may also decrease the effects of chlorothiazide; other commonly usednsaids nsaids and drugs interaction ; , including diclofenac cataflam, voltaren ; , etodolac lodine ; , fenoprofen nalfon ; , flurbiprofen ansaid ; , indomethacin indocin ; , ketorolac toradol ; , mefenamic acid ponstel ; , nabumetone relafen ; , oxaprozin daypro ; , piroxicam feldene ; , sulindac clinoril ; , and tolmetin tolectin oral antidiabetic drugs such as glipizide glucotrol ; , glyburide micronase, glynase, diabeta ; , chlorpropamide diabinese ; , tolazamide tolinase ; and tolbutamide orinase ; , which may not lower your blood sugar as well during therapy with chlorothiazide and reserpine your diabetes therapy may have to be adjusted lithium lithobid, eskalith, others ; , which should not be taken with chlorothiazide because serious side effects may result; or other drugs that also lower blood pressure, including acebutolol sectral ; , atenolol tenormin ; , bisoprolol zebeta ; , carteolol cartrol ; , labetalol trandate, normodyne ; , propranolol inderal ; , pindolol visken ; , timolol blocadren ; , benazepril lotensin ; , enalapril vasotec ; , captopril capoten ; , fosinopril monopril ; , lisinopril prinivil, zestril ; , moexipril univasc ; , quinapril accupril ; , ramipril altace ; , amlodipine norvasc ; , bepridil vascor ; , diltiazem cardizem, dilacor ; , felodipine plendil ; , isradipine dynacirc ; , nicardipine cardene ; , nifedipine adalat, procardia ; , nimodipine nimotop ; , and verapamil calan, veralan, isoptin and meprobamate.
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Prescribing Outlook is a national horizon scanning resource produced by UKMi. Part A, produced in collaboration with the NPC, gives information on drugs with market launches planned in the next 12-18 months. Part B estimates the impact of factors such as NICE guidance on prescribing budgets, and part C allows crude calculations of costs for local populations. These documents are available on-line to appropriate NHS staff. ukmi.nhs Med info PresOutlook
Before diagnoses of asthma among the elderly in a longitu dinal study of a general population sample. J Allergy7 Clin Immunol 1991; 88: 870-877 Ayres JG. Late onset asthma. BMJ 1990; 300: 1602-1603 Brown PJ, Greville HW, Finucane KE. Asthma and irrevers ible airflow obstruction. Thorax 1984; 39: 131-136 Bailey WC, Richards JM Jr, Rrooks CM, et al. Features of asthma in older adults. J Asthma 1992; 29: 21-28 Sobonya RE. Quantitative structural alterations in long standing allergic asthma. Rev Respir Dis 1984; 130 and mercaptopurine.
Accidents see Complications Acid-base equilibrium, hypocapnia and acidemia, influence on relaxation of tracheomotor tone by PEEP Byrick ; , 12 Age factors - anaesthesia for the geriatric patient: continuing medical education Desmeules etal. ; , 183 - cardiovascular response in geriatric patients during induction and intubation with low-dose fentanyl Chung and Evans ; , 622 - effect on meperidine sensitivity: abst. Herman et al. ; , 308 AIDS, see Immune system Airway - obstruction due to massive lingual oedema following cleft palate surgery: clinical report Lee and Kingston ; , 265 - response to histamine, effects of barbiturates and inhalation anaesthesia on: abst. Michoud et al. ; , S93 Alfantenil, see Analgesics Allergy - thrombocytopenia accompanying a reaction to protomane sulfate: clinical report Horrow ; , 49 Amiodarone, see Antiarrhythmics Anaesthesia - and head injury: refresher course outline Frost ; , S32 - arterial oxygenation during: refresher course outline Knill ; , S16 - automated, 380 - calcium channel blockers, implications for use of; continuing medical education Jenkins and Scoates ; , 436 - computers in: review article Zissos and Strunin ; , 374 - cardiac, stress free: refresher course outline Boulanger ; , S20 - cardiovascular - end-tidal carbon-dioxide tension and temperature changes after coronary artery bypass Donati et al ; , 272.
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Informational materials concerning hygiene, cleaning, floor care and laundry and concerning proper food safety practices and procedures with respect to cleaning of kitchens and food service equipment, proper floor care for commercial, industrial and institutional settings, and proper hygiene procedures for food service employees. Proposed Use in CANADA on services. Le droit l'usage exclusif du mot CLEAN en dehors de la marque de commerce n'est pas accord. SERVICES: Services de concierge; services d'hygine, de nettoyage, de polissage, de dsodorisation, de dsinfection et d'hygine publique dans les tablissements commerciaux, industriels et institutionnels; services d'entretien de plancher; services d'hygine de cuisine, de nettoyage de cuisine et de lavage des ustensiles de cuisine; services d'hygine et de nettoyage de toilettes; services de blanchisserie et de repassage; installation, rparation et entretien de machines de lavage de vaisselle, de lavage du verre, de schage de vaisselle et de schage du verre; installation, rparation et entretien de distributeurs; rparation et entretien d'appareils et de machines de nettoyage, de polissage et d'hygine publique; location d'quipement de nettoyage; services de nettoyage de vhicules; services de protection phytosanitaire; services pdagogiques et de consultation, nommment fourniture de formation, de sminaires, d'ateliers et de publications informatives concernant l'hygine, le nettoyage, l'entretien de plancher et la lessive, et concernant les pratiques et procds de scurit alimentaire appropris relativement au nettoyage des cuisines et de l'quipement pour la restauration collective, l'entretien de plancher appropri pour tablissements commerciaux, industriels et institutionnels, et procds d'hygine appropris pour employs de l'industrie de la restauration. Emploi projet au CANADA en liaison avec les services. 1, 150, 724. HP Intellectual Corp., c o John P. Garniewski, Jr., 2751 Centerville Road, Suite 352, Wilmington, Delaware 19803, UNITED STATES OF AMERICA Representative for Service Reprsentant pour Signification: GOWLING LAFLEUR HENDERSON LLP, 1 PLACE VILLE MARIE, 37TH FLOOR 37E ETAGE, MONTREAL, QUEBEC, H3B3P4 and meropenem.
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Food and Drug Administration. Nicotine in cigarettes and smokeless tobacco is a drug and these products are nicotine delivery devices under the Federal Food, Drug and Cosmetic Act: jurisdictional determination. Federal Register 61: 44619-45318, 1996.
Re-authorisation is the clinical responsibility of the doctor. While a doctor must be the one responsible for re-authorising prescriptions it is good practice to have reception staff involved to aid checking and mesna
| Meperidine duration of actionLudiomil ; or medicine for asthma or other breathing problems or medicines for colds, sinus problems, or hay fever or other allergies including nose drops or sprays ; or meperidine e, g.
702 hypothermia - and circulatory arrest for aortic arch aneurysm repair: clinical report Casthely et al. ; , 73 - cardio-pulmonary-bypass, influence on VO2 and CMRO2: abst. Murkin et al. ; , S63 inhalation agents, in cases of nemaline rod myopathy: clinical report Cunliffe and Burrows ; , 543 intravenous sedation in management of posterior lumbar osteotomy: clinical report Wills ; , 248 jet ventilation in bronchoscopy using paediatric fiberoptic bronchoscopes: technical report Sloan and McLeod ; , 79 laryngoscopy, clinical sign to predict difficult intubation in: clinical report Malampatti et al. ; , 429 management in major thermal injuries: continuing medical education Lamb ; , 84 nasogastric tube insertion during general anaesthesia, cardiovascular response to: clinical report Fassoulaki and Athanassiou ; , 651 nerve blocks around the thigh: abst. Hughes ; , S76 neuromuscular block, onset times of pancuronium and d-tubocurarine administered separately and combined: abst. Cashman et al. ; , 562 neuromuscular blocking agents, avoidance of, in cases of nemalin rod myopathy: clinical report Cunliffe and Burrows ; , 543 regional - axillary block, a method to improve success rate: abst. Culleriet etal. ; , S71 - anaesthetic indications for: conference summary Stock ; , 397 - brachial plexus block, supraclavicular, changes in lidocaine level and systemic effects of three concentrations of epinephrine on: abst. MacDonald etai ; , S67 - epidural, informed consent: correspondence Slusarenko and Noble ; , 681 - epidural in obstetrics, paresthesia and blood vessel cannulation caused by catheter insertion, effect of hyperventilation on: correpsondence Rolbin era . ; , 568 - medical indications for: conference summary Glassford ; , 396 - practical considerations: refresher course outline Houle ; , S47 - spinal, meperidine as the sole agent Famewo and Naguib ; , 533: abst. S75 - subarachnoid block - with lidocaine, changes in spinal cord blood following Kozody et al. ; , 472 and mesoridazine.
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020 CASE SERIES OF FIBROMYALGIA PATIENTS IMPROVED WITH ORAL CANNABINOIDS Dr. Gordon Ko MD CCFP EM ; FRCPC Dr. Annie Hum MD CAFCI Dr. Vincent Maida MD Michael Jokic Yr 3 student University of Toronto ; Introduction: This is the first reported case series of cannabinoid use in fibromyalgia. Case #1: A 50-year-old public health nurse, divorced mother-of-2, presented with longstanding "fibromyalgia". This included neck pain x 26 years, low back pain x 23 years, migraines x 13 years. Predisposing childhood factors included: growing pains, eating disorder, depression father died of Hodgkin's ; . Associated syndromes: costochondritis, plantar fasciitis, tendonitis, menopause. Non-helpful treatments included mobicox, amitriptyline, glucosamine, fish oil, guaifenesin naturopathy ; , massage, pool exercise, cognitive-behavioral and relaxation therapy. Temporary relief with toradol, robaxacet, acetaminophen, topical rubs, heating pad, chiropractic, osteopathy. She was allergic to meperidine and codeine. Cold made her worse. She declined acupuncture or injections. For migraines, she used migranal, zomig, fiorinal. L-tryptophan helped with sleep only. She never tried marajuana. Physical exam: BMI 38 5'7" 240lbs. ; , BP 120 80. 18 tender points. Positive tinel's with no neurologic deficit nor signs of connective tissue disease. Bone scan: degenerative changes: shoulders, ankles, feet, T10-12, L3-L5 facets. Ultrasound suggested borderline right CTS but EMG study was normal. Negative TOS doppler study. Beck depression score: 9 63. She was started on nabilone 1mg QHS. Her pain and stiffness were reduced. Side-effects included dizziness x 2 days, dry mouth x 1 week. After two weeks, the dose was increased to 1 mg BID. By 1 month, pain and headaches were further decreased. Pre-treatment: Two months later: VAS pain best to worse ; : 5-8 10 4-5 Fibromyalgia Impact Questionnaire 24.3 19.3 Tender point count 18 16 Average tender point pain threshold 2.18kg 2.6kg Other cases will be presented in detail suggesting that: Responders have low depression ratings, no previous adverse reaction to cannabinoids, and are employed. Poor responders include those with unstable psychiatric states, multiple environmental sensitivities, nondermatomal somatosensory deficits, on or seeking ; disability claims. Conclusion: Nabilone appears helpful as an adjuvant pain medication for carefully pre-screened fibromyalgia patients and metamucil.
At a counting efficiency of 28%. Protein was measured by the method of Lowry et al. 3 ; , with bovine-serum albumin as a standard. - ; -Naloxone was labeled by tritium exchange at the New England Nuclear Corp. 50 mg of naloxone were dissolved in 0.3 ml of trifluoroacetic acid with 50 mg of 5% Rh A1203 to which were added 25 Ci of 3H20, and the mixture was incubated 18 hr at 800. In our laboratory, a 70-mCi portion of [3H]naloxone was evaporated twice to dryness, and purified by thin-layer chromatography on Silica gel G plates MNKieselgel G uv 254 ; of 0.25-mm thickness n-butanol-glacial acetic acid-H20; 4: 1: 2 ; . When the purified [3H]naloxone was chromatographed in three additional solvent systems, the resulting single peak of radioactivity coincided with authentic naloxone, which was chromatographed beside it. The specific activity of [3H]naloxone was 6.1 Ci mmol of standard, as determined by comparison with the ultraviolet absorption of standard solutions of naloxone at 260 nm. Based upon this specific activity determination and a counting efficiency of 28%, 378 cpm is equivalent to 0.1 pmol of naloxone. Drugs were generously donated by the following companies: Endo naloxone, oxycodone Roche [levorphanol, dextrorphan, levallorphan, + ; -3-hydroxy-N-allyl-morphinan]; Lilly [ - ; - and + ; -methadone, + ; -propoxyphene]; Winthrop pentazocine cyclazocine, meperidine Reckitt and Colman, American Cyanamid Agricultural Division and Dr. William Martin, Lexington, Kentucky etorphine Knoll hydromorphone Ciba-Geigy etonitazene.
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Been stored in compliance with all Applicable Laws, has not been adulterated and has otherwise been maintained according to the requirements of Applicable Laws and Marketing Authorizations; D ; if Sanofi-Synthelabo notifies Atrix that Sanofi-Synthelabo does not intend to sell off any existing inventory of Product and utilize the Demonstration Samples, Sanofi-Synthelabo shall, at Atrix's election, either 1 ; sell all existing inventory of Product and Demonstration Samples to Atrix or 2 ; destroy all remaining inventory of Product and Demonstration Samples in accordance with Applicable Law, providing Atrix with proof of destruction in writing sufficient to comply with Applicable Laws; provided that in either case, Atrix shall pay to Sanofi-Synthelabo, the full amount of the actual cost paid by Sanofi-Synthelabo to Atrix, for such remaining inventory of Product and Demonstration Samples. If Sanofi-Synthelabo sells any inventory of Product or Demonstration Samples to Atrix pursuant to this subsection, it shall warrant that such inventory of Product and Demonstration Samples has been stored in compliance with all Applicable Laws, has not been adulterated and has otherwise been maintained according to requirements of Applicable Laws and Competent Authorities; and E ; any sales of Product or Demonstration Samples made by Sanofi-Synthelabo to Atrix pursuant to this Section 19.07 shall be made by Sanofi-Synthelabo within thirty 30 ; days of the end of the time period specified by Section 19.07 d ; ii ; and shall be shipped to Atrix appropriately packaged and stored. All transportation costs in connection with such sale, including without limitation, insurance, freight and duties, shall be shared equally by Sanofi-Synthelabo and Atrix. Amounts owed by Atrix to Sanofi-Synthelabo pursuant to this Section 19.07 d ; for the Product or Demonstration Samples shall be paid by Atrix within ten 10 ; days after receipt by Atrix of an appropriately detailed invoice from Sanofi-Synthelabo for the amount so owing to it by Atrix under this subsection. e ; Expiration or termination of this Agreement shall not relieve the Parties of any obligation accruing prior to such expiration or termination. Except as set forth below or elsewhere in this Agreement, the obligations and rights of the Parties under Sections 11.04, 14.07, 14.08 and Articles XII, XV, XVII and XX shall survive expiration or termination of this Agreement; provided that in the case of Section 4.05 d ; , such rights and obligations shall survive for only one 1 ; year after termination or expiration. f ; Within thirty 30 ; days following the expiration or termination of this Agreement, each Party shall return to the other Party, or destroy, upon the written request of the other Party, any and all Confidential Information of the other Party in its possession and upon a Party's request, such destruction or delivery ; shall be confirmed in writing to such Party by a responsible officer of the other Party. 40 and methadone.
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